• Bu D, Crewe C, Kusminski CM, Gordillo R, Ghaben AL, Kim M, Park J, Deng H, Xiong W, Liu XZ, Lonning PE, Halberg N, Rios A, Chang Y, Gonzalez A, Zhang N, An Z and Scherer PE. Human endotrophin as a driver of malignant tumor growth. Journal of Clinical Investigation Insight. 2019.03 (in press)


  • Yoon S, Nguyen HCT, Jo W, Kim J, Chi SM, Park J, Kim SY and Nam D. Biclustering analysis of transcriptome big data identifies condition-specific microRNA targets. Nucleic Acid Research. 2019.03 (in press)


  • Lee A, Jo S, Lee C, Shin HH, Kim TH, Ahn KJ, Park SK, Cho H, Yoon HK, Kim WG, Park J* and Choi Y*. Diabetes as a prognostic factor in HER-2 positive breast cancer patients treated with targeted therapy. Breast Cancer. 2019.03 (in press) Corresponding authors*


  • Alfadda AA, Sallam RM and Park J. Diet and nutrition for body weight management. Journal of Obesity. 2019.03;  2019, Article ID 6798096.


  • Lee C, Kim M, Lee JH, Oh J, Shin H, Lee SM, Scherer PE, Kwon HM, Choi JH, Park J*. COL6A3-derived endotrophin links reciprocal interactions among hepatic cells in the pathology of chronic liver disease. Journal of Pathology. 2019.01; 247(1)99-109


  • Lee JH, Suh JH, Choi SY, Kang HJ, Lee HH, Ye BJ, Lee GR, Jung SM, Kim CJ, Lee-Kwon W, Park J, Myung K, Park NH, Kwon HM.  Tonicity-responsive enhancer-binding protein promotes hepatocellular carcinogenesis, recurrence and metastasis.  Gut. 2019.02; 68(2)347-358


  • Park J, Kim M, Sun K, An YA, Gu X and Scherer, P.E.  VEGF-A expressing adipose tissue shows rapid beiging, enhanced survival after transplantation and confers IL4-independent metabolic improvements. Diabetes. 2017 June; 66(6) 1479-1490


  • Sun K*, Park J*, Kim M* and Scherer, P.E. Endotrophin, a multifaceted player in metabolic dysregulation and cancer progression, is a predictive biomarker for the response to PPARg agonist treatment.  Diabetologia. 2017 Jan; 60(1) 24-29. *co-first authors


  • Lee C, An D, and Park J. Hyperglycemic memory in metabolism and cancer. Hormone Molecular Biology and Clinical Investigation 2016 May; DOI:10.1515/hmbci-2016-0022
  • Choi S, Kim ES, Jung JE, Marciano DP, Jo A, Koo JY, Choi SY, Yang YR, Jang HJ, Kim EK, Park J, Kwon HM, Lee IH, Park SB, Myung KJ, Suh PG, Griffin PR, Choi JH. PPARγ antagonist Gleevec improves insulin sensitivity and promotes the browning of white adipose tissue. Diabetes. 2016; 65(4) 829-839


  • Choi S, Jung J, Yang YR, Kim E, Jang H, Kim E, Kim IS, Lee J, Kim J, Seo JK, Kim J, Park J, Suh PG, Choi JH. (2015) Novel phosphorylation of PPARγ ameliorates obesity-induced adipose tissue inflammation and improves insulin sensitivity. Cellular Signaling. 2015; 27:2488-2495


  • Ryu TY, Park J* and Scherer P.E* (2014) Hyperglycemia as a risk factor for cancer progression. Diabetes & Metabolism Journal. 2014; 38:330-336 *corresponding authors
  • Choi S, Park J and Choi J.H (2014) Revisiting PPARg as a target for the treatment of metabolic disorders. BMB Reports. 2014; 47: 599-608
  • Park J, Morely S.T, Kim M, Clegg D and Scherer P.E (2014) Obesity and Cancer: mechanisms underlying tumour progression and recurrence. Nature Reviews Endocrinology. 2014. Aug. (10)455-465. Doi:10.1038/nrendo.2014.94
  • Kim M, Neinast M, Frank A, Sun K, Park J, Zehr J, Vishvanath L, Morselli E, Amelotte M, Palmer B, Gupta R, Scherer P.E and Clegg D. (2014) ERα upregulates Phd3 to ameliorate HIF-1 induced fibrosis and inflammation in adipose tissue. Molecular Metabolism. 2014 Jun 7; 3(6):642-51.
  • Kusminski C.M, Park J and Scherer P.E. (2014) MitoNEET-Mediated Effects on Browning of White Adipose Tissue. Nature Communications. 2014. May. (5)3962. Doi: 10.1038/ncomms4962
  • Lackey DE, Burk DH, Ali MR, Mostaedi R, Smith WH, Park J, Scherer PE, Seay SA, McCoin CS, Bonaldo P, Adams SH. (2014) Contributions of adipose tissue architectural and tensile properties toward defining healthy and unhealthy obesity. Am J Physiol Endocrinol Metab. 2014 Feb. 306(3)E233-46


  • Park J, Morely T. S, and Scherer P.E. (2013) Inhibition of Endotrophin, a Cleavage Product of Collagen VI, Confers Cisplatin Sensitivity to Tumors. EMBO Molecular Medicine 2013 Jun;5(6):935-48
  • Ham M, Lee J, Choi A.H, Jang H, Choi G, Park J, Kozuka C, Masuzaki H, and Kim JB. (2013) Macrophage glucose-6-phosphate dehydrogenase stimulates proinflammatory responses with oxidative stress. Molecular Cellular Biology 2013 Jun;33(12):2425-35
  • Park J, and Scherer P.E. (2013) Endotrophin in the tumor stroma: a new therapeutic target for breast cancer? Expert Review of Anticancer Therapy. 13(2):111-113


  • Park J. and Scherer P.E. (2012) Endotrophin – a Novel Factor Linking Obesity with Aggressive Tumor Growth. Oncotarget. 3(12):1487-8
  • Park J, Sarode V, Euhus D, Kittler R, and Scherer P.E. (2012) The Neuregulin 1-HER Axis as a Key Mediator of Hyperglycemic Memory Effects in Breast Cancer. Epub 2012 Dec 3 Proc. Natl. Acad. Sci. USA.109(51):21058-63
  • Park J, and Scherer P. E. (2012) Adipocyte-derived endotrophin promotes malignant tumor progression. Journal of Clinical Investigation. 2012 Nov 1;122(11):4243-56. Epub 2012 Oct
    • Featured in the JCI Scientific Show Stoppers
    • Highlighted in the Research Highlights in Nature Reviews Cancer 12(11):p737(doi:10.1038/nrc3392) Nov. 2012
    • Highlighted in the Cover Story in Science-Business eXchange. Nature publishing group. Oct. 18. 2012 (doi: 10.1038/scibx.2012.1071)
    • Highlighted in the News in Cancer Discovery. Oct. 18. 2012 (doi. 10.1158/2159-8290.CD-RW2012-179)
  • Kusminski C.K, Holland W. L, Sun K, Park J, Spurgin S, Lin Y, Askew R, Simcox J. A, McClain D.A, Li C and Scherer P.E. (2012) MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity. Nature Medicine.2012 Sep 9; 18(10):1539-49. Doi:10.1038/nm.2899. Epub 2012 Sep 9.
    • Highlighted in the cover image. Cover image credit: David Gresham, Christine Kusminski, William Holland and Jiyoung Park. Cover designL Matt Hansen


  • Park J, and Scherer P.E. (2011) Leptin and Cancer: From Cancer Stem Cells to Metastasis. Endocrine-Related Cancer.Jul 11;18(4):C25-9.
  • Park J, Euhus D.M., Scherer P.E. (2011) Paracrine and Endocrine Effects of Adipose tissue on Cancer Development and Progression. Endocrine Reviews.32(4):550-70. Epub 2011 Jun 2
  • Lee JW, Choi AH, Ham M, Kim JW, Choe SS, Park J, Lee GY, Yoon KH, Kim JB. (2011) G6PD Up-Regulation Promotes Pancreatic {beta}-Cell Dysfunction. Endocrinology. 2011 Mar;152(3):793-803. Epub 2011 Jan 19


  • Park J, Kusminski C.M., Chua S. C. and Scherer P.E. (2010) Leptin receptor signaling supports cancer cell metabolism through suppression of mitochondrial respiration in vivo. American Journal of Pathology, 2010 Dec;177(6):3133-44. Epub 2010 Nov 5.
  • Landskroner-Eiger S, Park J, Israel D, Pollard JW, Scherer PE. (2010) Morphogenesis of the developing mammary gland: stage-dependent impact of adipocytes. Developmental Biology. 2010 Aug 15;344(2):968-78.

before 2009

  • Shin ES, Park J, Shin JM, Cho D, Cho SY, Shin DW, Ham M, Kim JB, Lee TR. (2008) Catechingallates are NADP+-competitive inhibitors of glucose-6-phosphate dehydrogenase and other enzymes that employ NADP+ as a coenzyme. Bioorganic & Medicinal Chemistry. 2008 Apr; 16(7):3580-3586.
  • Park J, Chung J and Kim JB (2007) New Insights of Redox Regulating System in Adipose Tissue of Obesity. Diabetes Research and Clinical Practice.2007 Sep;77Suppl 1:S11-6. Epub 2007 Apr 23.
  • Choe SS, Choi AH, Lee JW, Kim KH, Chung JJ, Park J, Lee KM, Park KG, Lee IK, Kim JB (2007) Chronic Activation of Liver X Receptor Induces b-cell Apoptosis through Hyperactivation of Lipogenesis. Diabetes. 2007 Jun;56(6):1534-43. Epub 2007 Mar 16
  • Park J, Choe SS, Choi AH, Kim KH, Yoon MJ, Suganami T, Ogawa Y, Kim JB (2006) Increase in Glucose-6-Phosphate Dehydrogenase in Adipocytes Stimulates Oxidative Stress and Inflammatory Signal. Diabetes.2006. Nov; 55(11): 2939-2949
  • Park J, Rho HK, Kim KH, Choe SS, Lee YS, Kim JB (2005) Overexpression of Glucose-6-Phosphate Dehydrogenase is Associated with Lipid Dysregulation and Insulin Resistance in Obesity. Mol. Cell. Biol. 2005. Jun; 25(12): 5146-5157
  • Rho HK, Park J, Suh JH, Kim JB. (2005) Transcriptional regulation of mouse 6-phosphogluconate dehydrogenase by ADD1/SREBP1c. Biochem. Biophys. Res. Commun.2005. Jun; 332(1):288-296
  • Cho HJ, Park J, Lee HW, Lee YS, Kim JB. (2004) Regulation of adipocyte differentiation and insulin action with rapamycin. Biochem. Biophys. Res. Commun. 2004. Sep; 321(4):942-948
  • Zhao C, Chen Y, Park J, Kim JB, Tang H. (2004) Tat-dependent repression of human immunodeficiency virus type 1 long terminal repeat promoter activity by fusion of cellular transcription factors. Biochem. Biophys. Res. Commun.2004. Sep; 322(2):614-622
  • Seo JB, Moon HM, Noh MJ, Lee YS, Jeong HW, Yoo EJ, Kim WS, Park J, Youn BS, Kim JW, Park SD, Kim JB. (2004) Adipocyte determination- and differentiation-dependent factor 1/sterol regulatory element-binding protein 1c regulates mouse adiponectin expression. J. Biol. Chem.2004. May; 279(21):22108-22117
  • Lee YS, Lee HH, Park J, Yoo EJ, Glackin CA, Choi YI, Jeon SH, Seong RH, Park SD, Kim JB. (2003) Twist2, a novel ADD1/SREBP1c interacting protein, represses the transcriptional activity of ADD1/SREBP1c. Nucleic Acids Res. 2003. Dec; 31(24):7165-7174
  • Seo JB, Noh MJ, Yoo EJ, Park SY, Park J, Lee IK, Park SD, Kim JB. (2003) Functional characterization of the human resistin promoter with adipocyte determination- and differentiation-dependent factor 1/sterol regulatory element binding protein 1c and CCAAT enhancer binding protein-alpha. Mol. Endocrinol.2003. Aug; 17(8):1522-1533
  • Park J. and Kim JB. (2002) Molecular Insights into Fat Cell Differentiation and Functional Roles of Adipocytokines. Kor. J. Endocrinology. 17: 1-9
  • Kim M, Lee W, Park J, Kim JB, Jang YK, Seong RH, Choe SY, Park SD. (2000) The stress-activated MAP kinase Sty1/Spc1 and a 3′-regulatory element mediate UV-induced expression of the uvi15(+) gene at the post-transcriptional level. Nucleic Acids Res.2000. Sep; 28(17):3392-3402